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| Meningitis vaccine: Santolaya and colleagues assess the immunogenicity and safety of a new vaccine, 4CMenB, a potential breakthrough in protection against meningitis, sepsis, and other infections caused by Neisseria meningitidis serogroup B. | Chikungunya: reviewing the clinical manifestations, treatment modalities, and re-emergence of this disease. | The myth of decreasing NHS productivity: there has been a fundamental misunderstanding of NHS productivity. |